PMID: 42167142
"SelO"ective NAD + hydrolysis regulates mitochondrial NAD + and homeostasis.
Zhang Qing, Min Tan Trina Chia, Sorrentino Vincenzo
Cell chemical biology · 2026
Research Library
NAD+
240 papers indexed
PMID: 42297284
1 H-NMR metabolomic profiling of Methanobacterium and Methanosarcina reveals unusual intracellular trimethylamine and acetamide production.
Jabłoński Sławomir Jan, Mielko-Niziałek Karolina Anna, Mori Kai et al.
Anaerobe · 2026
PMID: 42157495
19F NMR Probes of Conformational Change in a Bifurcating Electron Transfer Flavoprotein.
Priyadarshi Anurag, Miller Anne-Frances
Biophysical journal · 2026
PMID: 42420298
A metabolite-bridged complex between SerRS and SIRT2 couples NAD⁺ metabolism to translation control.
Zhang Qian, Zhang Huimin, Hirschi Marscha et al.
Nature communications · 2026
PMID: 42135894
A review of the sirtuins family: pivotal regulators and emerging therapeutic targets in renal fibrosis.
Deng Qiqi, Li Chaonian, Luo Jing et al.
Renal failure · 2026
PMID: 42573069
A self-iterative orthogonal base-editing platform enables multiplex N-to-N diversification and genome-scale functional screening in Escherichia coli.
Fan Xiangrui, Liang Liya, Wang Hongle et al.
Nucleic acids research · 2026
PMID: 42388370
AIE-pharmacology: Acacetin and NMN co-delivery rescues sperm motility.
Zhang Yujun, Zhao Fengfei, Sun Feiyi et al.
Materials today. Bio · 2026
PMID: 42458745
Accelerating Biocatalysis in Interface-Regulated Nano-Bio Hybrid System via Increasing Substrate Accessibility.
Xing Ziyang, Hua Kailiang, Li Rui et al.
ACS applied bio materials · 2026
PMID: 42389139
Acetylation as a dynamic regulatory interface between plant stress memory, cross-tolerance, and crop resilience design.
Ma Rongjin, Ruan Xianjue, Niu Xinchen et al.
Frontiers in plant science · 2026
PMID: 42427505
Acetylation-Primed SUMOylation Drives RORβ Turnover via a p300-SIRT1 Regulatory Axis.
O'Leary Timothy R, Shutin Denis, Montalvan Nadeska I et al.
bioRxiv : the preprint server for biology · 2026
PMID: 42427639
Adaptation of Methylobacterium extorquens to alternating carbon sources identifies the regulator CstR as an intersectional hub of cellular carbon metabolic dynamics and stress response.
Bruger Eric L, Ikobe Isabella, Hellenbrand Chandler N et al.
bioRxiv : the preprint server for biology · 2026
PMID: 42543917
Adaptation of White Adipocytes to Cooler Temperatures: Impacts on Energy Metabolism and Protein Acetylation.
Mori Hiroyuki, Hariri Hadla, Moe William et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
PMID: 42207018
Adaptive evolution of electron transfer pathways in Thermoanaerobacterium saccharolyticum .
Fabri João H T M, Huang Shu, Burgin T Emme et al.
Journal of bacteriology · 2026
PMID: 42428784
Aggregatibacter actinomycetemcomitans NadN contributes to neutrophil extracellular trap degradation.
Puanglai Yaowapa, Kasorn Anongnard, Matangkasombut Oranart et al.
Journal of oral microbiology · 2026
PMID: 42537805
Altered Gastrointestinal Function and Neurotensin Signaling in Experimental Type 2 Diabetes.
Öztürk Sudenaz, Kum Hilal, Sunuç Şevval et al.
Peptides · 2026
PMID: 42422067
Alternol inhibits GAPDH activity and disrupts glycolytic flux preferentially in cancer cells.
Chai Yuelong, Liu Wang, Mirza Moben et al.
Frontiers in pharmacology · 2026
PMID: 42173249
An ART-fold Rhs toxin from Pluralibacter gergoviae defines Tne5, a novel family of NAD(P) glycohydrolases effectors.
Desjardins Jonas B, Durrmeyer Martin, Bornet Olivier et al.
The Journal of biological chemistry · 2026
PMID: 42539049
An Acetylation-Primed SUMOylation Switch Controls RORβ Stability through a p300-SIRT1 Regulatory Axis.
Griffin Patrick, O'Leary Timothy, Shutin Denis et al.
Research square · 2026
PMID: 42576585
An Integrated Multi-Omics and Causal Inference Study Identifies a DNA Repair-Related Prognostic Biomarker in Gastric Cancer.
Yang Jianhua, Qiu Zheng, Song Wenchao et al.
Current medicinal chemistry · 2026
PMID: 42570950
An epigenetic switch in β-cells links mitochondrial stress to inflammatory fate via HMGB1 acetylation.
Cheng Yao, Wang Luyao, Bai Xue et al.
Cell death and differentiation · 2026
PMID: 42206755
An unexpected alternative viologen electron mediator site in tungsten-containing formate dehydrogenase.
Poloniataki Eleni G, Kim Yong Hwan
FEBS letters · 2026
PMID: 42294256
Antiaging Effects of Mannose-6-Phosphate through Enhanced Mitochondrial Function and Collagen Remodeling.
Munir Muniba, Zhang Mengxin, Khan Shahin Shah et al.
ACS omega · 2026
PMID: 42165863
Assessment of methylene blue and NAD on LPS-induced acute brain injury: effects on neuroinflammation, oxidative stress, and blood-brain barrier integrity in a rat endotoxemia model.
Doganay Songul, Üstündağ Hilal, Erbaş Elif et al.
Naunyn-Schmiedeberg's archives of pharmacology · 2026
PMID: 42575897
Author Correction: High-resolution mapping reveals features of bacterial NAD-capped RNAs and stress-responsive transcription initiation.
Zhang Hailei, Qi Yinyao, Li Qiongfang et al.
Nature communications · 2026
PMID: 42137595
Autofluorescence imaging reveals the impact of cryopreservation on T cell metabolism and activation response.
Pham Dan L, Kalluri Meghana, Weaver Cole et al.
Molecular therapy. Advances · 2026
PMID: 42502305
Autophagy-Related Gene-Set Signals in the Genetic Architecture of Obsessive-Compulsive Disorder: A Hypothesis-Generating Link to Nicotinamide Adenine Dinucleotide-Associated Cellular Maintenance Biology.
Cheung Ngo
Cureus · 2026
PMID: 42424438
Bacteria sense virus-induced genome degradation via methylated mononucleotides.
Osterman Ilya, Hurieva Bohdana, Moses Sarit et al.
Science (New York, N.Y.) · 2026
PMID: 42214335
Bacterial defense via RES-mediated NAD + depletion is countered by phage phosphatases.
Osterman Ilya, Hurieva Bohdana, Yirmiya Erez et al.
Cell host & microbe · 2026
PMID: 42292186
Beyond cartilage degeneration: osteoarthritis as a systems failure of inflammation regulation.
Bar-Or David, Williams Jason, Hausburg Melissa et al.
Frontiers in medicine · 2026
PMID: 42163139
Beyond deacetylation: crosstalk mechanisms and context-dependent regulation of sirtuin non-classical enzymatic functions in disease.
Ma Yiran, Chen Junli, Song Ruixiao et al.
Molecular medicine (Cambridge, Mass.) · 2026
PMID: 42135764
Bi-directional regulation between NAD/NAMPT and IFN-γ/PD-L1 axes via BRD4/IRF1 and mitochondrial respiration in metastatic cutaneous melanoma.
Fiorilla Irene, Ghezzi Beatrice, Ponzano Alessia et al.
Journal of experimental & clinical cancer research : CR · 2026
PMID: 42247007
Biochanin A enhances wound healing in diabetic rats: emphasis on antioxidant, anti-inflammatory, angiogenic and pro-collagen activities.
AlGhamdi Abeer S, Alkinani Khadijah B, Abdel-Naim Ashraf B et al.
Naunyn-Schmiedeberg's archives of pharmacology · 2026
PMID: 42324044
Biosensor-driven adaptive laboratory evolution and modular pathway engineering for high-level production of nicotinamide mononucleotide in yeast.
Shi Ruirui, Han Qiancheng, Xu Yingxue et al.
Bioresource technology · 2026
PMID: 42579050
Boron as a Context-Dependent System-Level Modulator: Mechanisms and Implications in Chronic Diseases.
Tuzcu Mehmet, Ozmen Ramazan, Ali Shakir et al.
Biological trace element research · 2026
PMID: 42135394
Brain metabolomic profiling reveals ischemia-dominant disruption of metabolic pathways and tissue homeostasis in neonatal hypoxic-ischemic brain injury.
Wolff Nora, Triantafyllou Maria, Ghaemmaghami Javid et al.
Scientific reports · 2026
PMID: 42292426
CD38+ NK cells: novel players in immunoregulation.
Chang Xiaotian, Fang Kehua
Frontiers in immunology · 2026
PMID: 42385602
CD38-driven NAD⁺ depletion governs crypt structure and barrier dysfunction in fluorouracil-induced colonic mucositis: From metabolic collapse to architectural remodeling.
Elmorsy Elsayed A, Hamad Rabab S, Alorini Mohammed et al.
Tissue & cell · 2026
PMID: 42382756
Calibrating microglia states in Alzheimer's disease: decoding immune-metabolic networks and nano-targeted multicomponent therapies.
Xing Jin Feng, Mu Kaijin, Yan Xue et al.
Frontiers in immunology · 2026
PMID: 42384769
Carbon monoxide-releasing vesicles provide rapid and sustained inhibition of inflammatory pain in mice.
Bárcena-Esplá Alejandra, López-Martín Mario, Negrini-Ferrari Sylmara Esther et al.
Journal of liposome research · 2026
PMID: 42426488
Cell-Type-Specific Calibration of Mitochondrial Ubiquitination in Stem Cell Fate Decisions.
Liu Hao-Cheng, Chen Si-Yuan, Yu Nan-Nan et al.
Stem cell reviews and reports · 2026
PMID: 42529685
Cellular Logistics and Synaptic Vesicle Vulnerability in Major Depressive Disorder and Amyotrophic Lateral Sclerosis Comorbidity: Insights From Nicotinamide Mononucleotide Rescue and Transcriptome-Wide Association Study Integration.
Cheung Ngo
Cureus · 2026
PMID: 42167559
CgHb-like modulates the energy metabolism, histone acetylation and inflammatory responses in oysters during Vibrio splendidus stimulation.
Wang Jie, He Muchun, Leng Jinyuan et al.
Fish & shellfish immunology · 2026
PMID: 42391652
Chlorination-driven redox metabolic reprogramming promotes bacterial persistence and cross-resistance in drinking water systems.
Wang Mengyuan, Niu Zhiguang, Zuo Xin et al.
Water research · 2026
PMID: 42244013
Circulating CD38 shows stronger association with incident heart failure in women despite lower levels: sex differences and kidney-function context.
Mprah Richard, Machuki Jeremiah Ong'Achwa, Wowui Prosperl Ivette et al.
Biology of sex differences · 2026
PMID: 42128264
Combined exposure to T-2 and HT-2 Mycotoxins Induces Ferroptosis through Down-regulation of SLC7A11/GPX4 and NAD(P)H/FSP1/CoQ10 Pathways in Caco-2 Cells.
Zhao Hanke, Guo Wenbo, Wang Jie et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2026
PMID: 42535757
Common and Particular Biochemical Effects of Gadolinium and Yttrium in the Bivalve Mollusc Unio tumidus.
Khoma Vira, Yunko Kateryna, Martyniuk Viktoriia et al.
Journal of applied toxicology : JAT · 2026
PMID: 42301268
Compartmentalized Encapsulation of Rhodium-Alginate Conjugate in Hybrid Hydrogen-Bonded Organic Frameworks for In Situ Cofactor Recycling and Biocatalysis.
Guo Ranran, Sun Yan
ACS applied materials & interfaces · 2026
PMID: 42385930
Conditional Knockout of Indoleamine 2, 3-Dioxygenase-1 in Osteoprogenitor Cells in Mice Results in Sex-dependent Differences in Bone Mass.
Kang Baolin, Bollag Wendy B, Buxeda Diego et al.
Biochimie · 2026
PMID: 42469088
Corrigendum to "Correlation of NADH/NAD+ electrochemical potential and enzymatic activity for investigating protein folding and kinetics" [Biochem. Biophys. Res. Commun. 750 (2025) 151393].
Sinha Anurag, Singh Ashish K, Sharma Supriya et al.
Biochemical and biophysical research communications · 2026
PMID: 42299234
Cross-Disorder Pruning-Plasticity-Aging Architecture in Substance Use Disorders and Anxiety: Transcriptome-Wide Association Insights and Mechanistic Synthesis.
Cheung Ngo
Cureus · 2026
PMID: 42296784
DHRS9 knockdown attenuates severe acute pancreatitis by inhibiting ferroptosis through the modulation of redox homeostasis and oxylipin metabolism.
Yu Tingfeng, Tan Ning, Ma Mingzhe et al.
International immunopharmacology · 2026
PMID: 42420530
Deacetylation of SRF catalyzed by SIRT7 protects against abdominal aortic aneurysm formation.
Xiong Yacheng, Chen Jing, Lu Weiting et al.
Experimental & molecular medicine · 2026
PMID: 42579127
Decabromodiphenyl Ethane Sensitizes Zebrafish to Alcoholic Liver Injury by Compromising NAD+-Mediated Multicellular Responses.
Li Fan, Yang Lihua, Zhang Yindan et al.
Environmental science & technology · 2026
PMID: 42543141
Decoding Context-Dependent Sirtuin Pharmacology in Cancer: Metabolic-Epigenetic Switches and Precision Therapeutic Targeting.
Aly Abdelwahab, Zhiqing Tan, Sasidharan Sreenivasan et al.
Critical reviews in oncology/hematology · 2026
PMID: 42291131
Design and synthesis of a tetraphenylethene-porphyrin hetero-faced molecular cage for photodynamic therapy.
Fan Jiaxi, Li Zhuoxia, Cheng Lin et al.
National science review · 2026
PMID: 42571909
Developing a Novel Fluorescent Probe for Selectively Recognizing NQO1 in Cancer Cells and at the Tail Amputation Site of Zebrafish.
Sun Shiran, Ji Yuan, Chen Gesong et al.
Luminescence : the journal of biological and chemical luminescence · 2026
PMID: 42420230
Development of Metabolic Stress in Vascular Organoids under Normal Conditions and with AD/PD-Associated Genetic Backgrounds.
Blagova Anna V, Perepelitsa Elizaveta S, Satish Anakha et al.
Biochemistry. Biokhimiia · 2026
PMID: 42467120
Differential NAD + availability may drive asymmetric SIRT7 activity in tumor and immune cells.
Lagunas-Rangel Francisco Alejandro
Molecular biology reports · 2026
PMID: 42258953
Disinfectant quaternary ammonium compounds hijack the NAMPT-NAD⁺ axis to impair trophoblast function.
Fang Yongbao, Zhao Ailin, Fang Yuanyuan et al.
Environment international · 2026
PMID: 42571812
Disruption of progesterone synthesis by PBDEs: Potent inhibition of human and rat placental 3β-hydroxysteroid dehydrogenase by the metabolite 4-Bromodiphenyl ether.
Xie Lubin, Fei Qianjin, Su Ming et al.
Toxicology and applied pharmacology · 2026
PMID: 42381240
Domino Effect of the Kynurenine Pathway: Systemic Homeostasis, Metabolic Crosstalk, and Therapeutic Potential.
Ma Pei-Jun, Man Yi-Chen, Shen Fang-Qing et al.
Comprehensive Physiology · 2026
PMID: 42206993
Dose-Dependent Effects of Dihydronicotinamide Riboside on Human Engineered Skeletal Muscle Development.
Venkateshvaran Ashwin, Pundlik Swarang Sachin, Suresh Yavanica et al.
ACS biomaterials science & engineering · 2026
PMID: 42211890
Downregulation of FLT1 delays vascular aging by suppressing MAPK signaling pathway activation in vascular smooth muscle cells​.
Fu Li, Duan JingFeng, Ge Min et al.
Cytotechnology · 2026
PMID: 42462379
Dual-targeted pH-responsive nanoliposome (M5/NMN/DEAP/iRGD-Lip): Immunostimulatory-photodynamic synergy for breast cancer therapy.
Zhuang Junwei, Guo Chen, Ye Xingming et al.
Colloids and surfaces. B, Biointerfaces · 2026
PMID: 42533867
Dynamic Profiling and Screening of Cancer Starvation-Immunotherapy Regimens via a Cross-Referencing Multispectral Upconversion and Tomographic Photoacoustic Imaging Nanoprobe.
Ye Minan, Li Yuanjun, Deng Handi et al.
Small (Weinheim an der Bergstrasse, Germany) · 2026
PMID: 42529306
Dysregulation of the Glycolytic Entry Gate and Survival Route by Advanced Lipoxidation End Products in Diabetes Mellitus.
Mondal Anwesa, Pramanik Subhasish, Bose Chiranjit et al.
Journal of ophthalmology · 2026
PMID: 42246550
EXPRESS: Dezocine Allevates Cancer-Induced Bone Pain and Suppresses Intraosseous Tumor Growth in Renal Cell Carcinoma via the NAMPT/NAD+ Axis.
Huang Lijun, Hu Cixian, Shao Ya et al.
Molecular pain · 2026
PMID: 42141362
Effect of Sevelamer and B. longum on Insulin Sensitivity in Participants With Obesity: A Randomized Clinical Trial.
Baeuerle Eric, Semwal Manpreet K, Nie Jia et al.
Obesity (Silver Spring, Md.) · 2026
PMID: 42248364
Effects of Weak Organic Acid Salts on Growth Kinetics of Spoilage-Associated Lactic Acid Bacteria in Cured Ready-to-Eat Turkey Breast.
Dogan Mehmet, Milkowski Andrew L, Sindelar Jeffrey J
Journal of food protection · 2026
PMID: 42339178
Effects of dinotefuran and its metabolites on the early life stage development of medaka ( Oryzias latipes ): In vivo and in silico studies.
Hirano Masashi, Inoue Daishi, Uchida Masaya et al.
Toxicology reports · 2026
PMID: 42243613
Efficacy and Mechanism of Silymarin Extract for Deep Second-Degree Burns in Rats.
Zhang Xue, Yuan Yong, Wang Zi-Qiang et al.
Chinese journal of integrative medicine · 2026
PMID: 42214936
Electro-driven microbial conversion of waste carbon sources to polyhydroxyalkanoates: pathways, mechanisms, and prospects.
Pan Xuwei, Zhang Yuchen, An Wenhui et al.
Journal of environmental management · 2026
PMID: 42469212
Emerging roles of SIRT6 and its modulators in kidney diseases.
Ren Feihong, Wang Yudian, Zhang Yufei et al.
Cell death discovery · 2026
PMID: 42130227
Engineering a Novel Cofactor-Versatile Short-Chain Dehydrogenase for Efficient Synthesis of Chiral Alcohols.
Yao Li-Li, Song Xian-Heng, Huang Kai-Cheng et al.
Biotechnology and bioengineering · 2026
PMID: 42297193
Environmental factors modulate the responsiveness and reversibility of the H 2 O 2 -induced inactivation of GAPDH.
Boms Kirsty, Jørgensen Sara M, Hägglund Per et al.
Free radical biology & medicine · 2026
PMID: 42572165
Enzymatic Determination of D-Malic Acid in Selected Foods: AOAC Official Method 2026.02 First Action.
Lacorn Markus, Hektor Thomas
Journal of AOAC International · 2026
PMID: 42258046
Enzymatic Synthesis of NAD .
Boyle Emily, Zhang Olivia, Cen Yana
Current protocols · 2026
PMID: 42326687
Evidence for the Formation of Metabolons Surrounding the Pyruvate Node in the Supercritical CO 2 ‑Tolerant Priestia megaterium SR7.
Yu King Hing Nathaphon, Chang Yi Wen Kristy, Vethathirri Ramanujam Srinivasan et al.
ACS omega · 2026
PMID: 42256794
Evolutionary divergence of nocturnin led to redox regulation in mammalian orthologs.
Olivas-Rasmussen Crystal A, Gao Peng, Rasmussen Emil S et al.
Biochemistry and biophysics reports · 2026
PMID: 42290027
Exercise-Induced Extracellular Vesicles as Mediators of Mitochondrial Biogenesis and Insulin Sensitivity in Metabolic Adaptation.
Wang Jian, Wu Lei
Endocrinology, diabetes & metabolism · 2026
PMID: 42385907
Exogenous S 0 enhances the degradation of lignocellulose residues in anaerobic digestion: by driving the coenzyme A-dependent NAD(P)H sulforeductase pathway and persulfidation modification of cellulase.
Qiao Zihao, Chen Zezhi, Gong Huijuan et al.
Bioresource technology · 2026
PMID: 42218329
Exploiting DprE2 pathway redundancy to enhance potency and overcome resistance to pretomanid in Mycobacterium tuberculosis.
Djaout Kamel, Dreneau Aurore, Faion Léo et al.
npj antimicrobials and resistance · 2026
PMID: 42214696
Expression and functional role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in glycidyl methacrylate-induced malignant transformation of lung epithelial cells.
Liu Xintong, Wu Hongjiao, Cui Yishuang et al.
Toxicology and applied pharmacology · 2026
PMID: 42499152
Extending Cofactor-Tethered Nanomachines to Complex Multienzyme Redox Cascades in Continuous Flow.
Dsouza Zinnia, Friedrichs Jan-Simon Jeshua, Melse Okke et al.
ChemSusChem · 2026
PMID: 42217683
Extracellular Lactate Reprograms Mitochondrial Metabolism and NAD + /NADH Redox Balance in Blood-Brain Barrier Endothelial Cells via an LDHB-MPC-NAD + Axis.
Jain Charul, Kuzmychova Helgi, Grewal Akaljot et al.
Free radical biology & medicine · 2026
PMID: 42460335
FLIM quantification of temperature-dependent enzyme-NADH binding dynamics.
Martinez Jocelyn, Theodossiou Anna, Hu Linghao et al.
Biomedical optics express · 2026
PMID: 42500827
Factors Determining Sirtuin-1 Target Engagement.
Neumann-Staubitz Petra, Burgdorf Yannick, Hofmann Sarah et al.
Advanced biology · 2026
PMID: 42492338
Feeding the epigenome: EZH2 as a metabolic integrator of cell fate in development and cancer.
Ansari Suraiya Anjum, Emerald Bright Starling
Molecular aspects of medicine · 2026
PMID: 42157898
Free energy relationship analysis for temperature dependence of hydride kinetic isotope effects of NADH/NAD + model reactions: implication for barrier compression by enzyme dynamics.
Austin-Kloppe Ava, DeGroot Nicholas, Dhakal Bikram et al.
Chemical science · 2026
PMID: 42166869
From DNA repair to neurodegeneration: PARP1 mechanisms and inhibitor strategies in Alzheimer's disease.
Banjare Purusottam, Patel Richa
DNA repair · 2026
PMID: 42537461
Galangin attenuates UVB-induced skin photoaging through SIRT1-dependent LC3 deacetylation and autophagy modulation.
Wen Su-Ying, Ng Shang-Chuan, Su Mei-Hsin et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology · 2026
PMID: 42129495
Genomic heterogeneity of NAD(P)H dehydrogenase predisposes Cryptosporidium to clofazimine resistance.
Buenconsejo Gracyn Y, Shaw Sebastian, Xiao Rui et al.
Nature microbiology · 2026
PMID: 42247019
Glucose metabolism and transcriptional responses to vitamin B6 in tau-expressing fission yeast cells.
Yilmazer Merve, Karaer Uzuner Semian, Palabiyik Bedia
Molecular biology reports · 2026
PMID: 42551374
Glycitein-mediated rhizosphere signaling recruitment and CobB deacetylation synergistically enhance fomesafen bioremediation by Klebsiella variicola W28.
Wu Yulin, Liu Kuo, Ding Yubo et al.
Journal of hazardous materials · 2026
PMID: 42571403
Glycolytic reprogramming and the EMT drive cervical cancer progression via the NQO1/HIF1α-SIX1 axis.
Zhu Guang, Piao Zhenggen, Gao Yuan et al.
iScience · 2026
PMID: 42462419
Guizhi Wuling Decoction alleviates myocardial fibrosis by restoring mitochondrial homeostasis: Evidence from network pharmacology, molecular docking, and multi-omics integration.
Shi Lipeng, Wang Jie, Yang Ruogu et al.
Journal of ethnopharmacology · 2026
PMID: 42247013
HM568 Enhances NAD + Biosynthesis to Ameliorate Mitochondrial Dysfunction and Neurotoxicity in Parkinson's Disease Models: A Putative Link to PARP1 Modulation.
Li Minpeng, Li Wei, Liu Yingjie et al.
Molecular neurobiology · 2026
PMID: 42427725
Heat stress drives opposing redox shifts in temperate versus tropical Drosophila melanogaster embryos.
O'Leary Thomas S, Lockwood Brent L
bioRxiv : the preprint server for biology · 2026
PMID: 42162655
High susceptibility of mouse hepatic Cyp2a to the inactivation by oral imperatorin: isoform sensitivity and tissue specificity.
Chih Jia-Shan, Liu Jie-Ting, Liaw Chia-Ching et al.
Chemico-biological interactions · 2026
PMID: 42501188
Histone lactylation inhibits Slc25a51 expression and thus promotes collagen dysregulation of pelvic organ prolapse through impairing mitochondrial NAD + transport.
He Yong, Liu Cheng, Li Bingshu et al.
Science China. Life sciences · 2026
PMID: 42135539
Human whole-blood NAD + levels do not vary with age or lifestyle interventions.
Trętowicz Maria M, Scantlebery Angelique M L, Schomakers Bauke V et al.
Nature metabolism · 2026
PMID: 42218107
Identification of alcohol dehydrogenase (ADH) isoforms catalyzing hydroxyzine oxidation using recombinant human ADH: Serendipitous finding of potent ADH inhibition by organic solvents.
Tonami Takuya, Sato Rei, Nakano Masataka et al.
Drug metabolism and disposition: the biological fate of chemicals · 2026
PMID: 42461545
Immobilization of Nicotinamide Adenine Dinucleotide Cofactors Using Aryl Diazonium Electrografting.
Abdellaoui Sofiene
Methods in molecular biology (Clifton, N.J.) · 2026
PMID: 42335646
Immune metabolic remodeling during exercise rehabilitation: Linking skeletal muscle regeneration, bone homeostasis, and systemic immune adaptation.
Wang Fei, Qin Wenjie
Tissue & cell · 2026
PMID: 42164494
Immunometabolic control of cytokine production by micronutrients in health, aging, and inflammation.
Ghosh Joyeta, Chattopadhyay Debprasad
Frontiers in immunology · 2026
PMID: 42132646
In vivo 2D-IR spectroscopy of [NiFe] hydrogenases: a shielding role of the protein matrix.
Vaithiyanathan Mathesh, Bernitzky Cornelius C M, Poire Denise et al.
Physical chemistry chemical physics : PCCP · 2026
PMID: 42469666
Inflammatory mediators are predictors of clinical outcomes in cirrhotic patients with non-acute decompensation.
Wang Xixuan, Shen Jiale, Guo Jun et al.
BMC gastroenterology · 2026
PMID: 42335895
Integrated control of redox and energy metabolism by the membrane-bound and soluble transhydrogenases of Pseudomonas putida across metabolic regimes.
Partipilo Michele, Favoino Giusi, Puiggené Òscar et al.
Cell systems · 2026
PMID: 42159653
Intracellular NAD + Depletion Increases Prostanoid Production via p38/COX2 Signalling in FK866-Induced Senescent Human Umbilical Vein Endothelial Cells.
Kitajima Natsuko, Nakajo Takahisa, Katayoshi Takeshi et al.
Journal of cellular and molecular medicine · 2026
PMID: 42170234
Ion-coupled transfersome complexes for enhanced transdermal NAD + repletion and mitigation of cellular senescence signatures.
Kang Seongsu, Wei Shibo, Koo Bon Il et al.
Materials today. Bio · 2026
PMID: 42457865
Label-free segmentation of mitochondria for simultaneous morphological and metabolic studies.
Bae Kideog, Özbey Muzaffer, Ho Alexander et al.
Communications biology · 2026
PMID: 42459936
Linking SIRT1 gene variation and protein levels to the pathophysiology of type 2 diabetes.
Hasan-Idan Hayder, Kohan Leila
Molecular biology research communications · 2026
PMID: 42545560
Liraglutide affects mitochondrial function and histone acetylation through the NQO1/SIRT3 pathway in diabetic kidney disease.
Gao Jie, Lv Xiaoyu, Zhao Pingping et al.
Molecular and cellular biochemistry · 2026
PMID: 42297727
Long-Term Risk of Allergic Contact Dermatitis in Children With Atopic Respiratory Disease When They Reach Adulthood.
De Marchi Sergio, Cecchin Emanuela, De Marchi Sergio Umberto et al.
Contact dermatitis · 2026
PMID: 42469197
MAP2K6 reprograms NAD + metabolism via the HMGA1-NAMPT axis to sensitize ovarian cancer cells to PARP inhibition.
Wen Ming, Chen Zhuohang, Zhan Dongdong et al.
Cell death & disease · 2026
PMID: 42575457
MCART1 (SLC25A51) deficiency exacerbates mitochondrial dysfunction during MPP + -induced complex I stress.
Wang Shiliang, Sun Peixin, Zhang Yue et al.
Free radical biology & medicine · 2026
PMID: 42468364
Making waves: The overlooked role of non-antibiotic drugs in driving antibiotic resistance gene dissemination.
Chen Xinqiang, Liu Yongqin, Zhou Shaofeng et al.
Water research · 2026
PMID: 42206981
Mapping the Subtype-Specific PARP1 ADP-ribosylated Proteome in Breast Cancer Cells.
Koul Sneh, Kwon Minjung, Tapadar Poulami et al.
Molecular cancer research : MCR · 2026
PMID: 42332248
Mavacamten improves energy balance in a pre-clinical model of RASopathy-associated hypertrophic cardiomyopathy.
Ruiz-Velasco Andrea, Jouve Charlène, Deshayes Lucille et al.
Pediatric research · 2026
PMID: 42329469
Mechanistic and functional integration of sirtuin deacylases: from substrate specificity to biological outcomes.
Zhang Jian-Long, Dou Zi-Yu, Fan Yong-Yue et al.
Glycoconjugate journal · 2026
PMID: 42534639
Mechanistic intersections of empagliflozin and nebivolol in aging-associated redox and inflammatory pathways.
Al-Mahdawi Mohammed Akram, Fawzi Hayder Adnan, Ibrahim Nurul'Izzah et al.
Frontiers in pharmacology · 2026
PMID: 42252065
Membrane Instability as a Propagation-Repair Imbalance in Ferroptosis.
Lee Jaewang, Roh Jong-Lyel
Free radical biology & medicine · 2026
PMID: 42162555
Metabolic Plasticity in Embryogenesis Throughout the Lens of NAD .
Escalante-Covarrubias Quetzalcoatl, Delgado-Olguín Paul
Methods in molecular biology (Clifton, N.J.) · 2026
PMID: 42384665
Metabolic profiling of human melanoma cell lines with high and low metastatic capacity by 1H-NMR spectroscopy.
Kakhki Nima Rezvani, Hegedűs Zita, Tóvári József et al.
PloS one · 2026
PMID: 42380285
Metabolic reprogramming of myeloid cells in cancer: from lactate-NAMPT axis to AI-guided therapeutics.
Lee In-Gu, Jung Keehoon
Experimental & molecular medicine · 2026
PMID: 42552038
Metabolic therapeutic targets in Alzheimer's disease.
Peter L Ignatius Raymond, Chatterjee Debojyoti, Chrishone A Froilanmark et al.
International review of neurobiology · 2026
PMID: 42537919
Metals exposure dissociates mitochondrial NAD(P)H redox state from H₂O₂ emission.
Tetteh Pius Abraham, Kalvani Zahra, Stevens Don et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2026
PMID: 42250161
MicroRNA-SIRT1 crosstalk in liver diseases: molecular regulation of metabolism, inflammation, and cell survival.
Abdelgawwad El-Sehrawy Amr Ali Mohamed, Radhie Safa H, Baig Mirza R et al.
Molecular biology reports · 2026
PMID: 42491760
Microbial predictors of sustained clinical remission following the Crohn's disease exclusion diet in adults and microbiome shifts toward healthy pediatric controls.
Sigall-Boneh Rotem, Organ Sarah, Ghiboub Mohammed et al.
Crohn's & colitis 360 · 2026
PMID: 42546117
Mitochondria-targeted therapeutic strategies in assisted reproduction: challenges and potential solutions.
Yildirim Raziye Melike, Sahin Gizem Nur, Scott Richard T et al.
Human reproduction (Oxford, England) · 2026
PMID: 42331132
Mitochondrial Alterations and CKD.
Pinzon-Cortes Jairo A, Narongkiatikhun Phoom, Yuan Long et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026
PMID: 42162436
Mitochondrial L-2-hydroxyglutarate is a physiological signalling metabolite.
Chakrabarty Ram P, Van Vranken Jonathan G, Aoi Yuki et al.
Nature · 2026
PMID: 42209413
Mitochondrial NAD + Transport Alleviates Cerebral Ischemia/Reperfusion Injury via Enhancement of Mitochondrial Function.
Wang Xiaorong, Li Yuxin, Tan Jinhua et al.
Antioxidants & redox signaling · 2026
PMID: 42172306
Mitochondrial complex I activity promotes antigen cross-presentation in dendritic cells.
Khouili Sofía C, Priego Elena, Heras-Murillo Ignacio et al.
Science immunology · 2026
PMID: 42209503
Mitochondrial drivers of stem cell aging and inflammaging.
Bautista Jhommara, López-Cortés Andrés
npj aging · 2026
PMID: 42429759
Mitochondrial localization of key NAD + -dependent dehydrogenases explains the exceptionally high biomass yield on ethanol of the yeast Cyberlindnera jadinii .
Warmerdam Marieke, Pijman Yared O, Pedersen Marc P et al.
Applied and environmental microbiology · 2026
PMID: 42497772
Mitochondrial-targeted nano-enhancer driving a self-amplifying NAD + feedback loop to reprogram MSC spheroids metabolism for accelerated bone regeneration.
Li Hailong, Liu Xifeng, Li Wenkai et al.
Biomaterials · 2026
PMID: 42324299
Model-driven analysis reveals oxidative stress adaptation enabling efficient energy utilization in a Crabtree-negative Saccharomyces cerevisiae.
Tafur Rangel Albert, Castillo García Andrés, Malina Carl et al.
Scientific reports · 2026
PMID: 42136641
Modulating CD38 enzymatic activity during antibody-based immunotherapy in multiple myeloma: a basic science perspective.
Horenstein Alberto L, Frerichs Kristine A, Faini Angelo C et al.
Frontiers in immunology · 2026
PMID: 42337422
Molecular mechanisms of FSP1-regulated ferroptosis and therapeutic implications in various cancers.
Zhang Congyue, Sun Chao, Nan Yuemin
Cellular & molecular biology letters · 2026
PMID: 42468593
Multi-module immobilization of Gluconobacter frateurii alcohol dehydrogenase and Lactobacillus brevis NADH oxidase with tethered nicotinamide adenine dinucleotide for D-allulose biosynthesis.
Ai Jiaying, Yan Jiajun, Zhang Yuxin et al.
International journal of biological macromolecules · 2026
PMID: 42332562
Multi-omics unveils seasonal remodeling and metabolic crosstalk between testis and abdominal fat body in a non-amplexus stream frog Nanorana taihangnica (Anura: Dicroglossidae).
Zhang Yimin, Zhao Ruinan, Yang Xinyue et al.
BMC genomics · 2026
PMID: 42128705
Multidimensionally engineered Escherichia coli for efficient gadusol biosynthesis with high-throughput quantitative analysis.
Zhang Ping, Zhang Weijiao, Xiong Haibo et al.
Trends in biotechnology · 2026
PMID: 42575273
Multiple manifestations of coronary microvascular dysfunction in a double-hit mouse model of HFpEF.
Kwiatkowski Grzegorz, Tyrankiewicz Urszula, Mosiołek Sylwester et al.
Vascular pharmacology · 2026
PMID: 42294794
NAD + Metabolism Licenses Zygotic Genome Activation via PARP7-Mediated ADP-Ribosylation of UHRF1 in Mouse Early Embryos.
Cao Guangyi, Zhang Ziqi, Chen Anqi et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
PMID: 42329791
NAD + metabolism at the host-virus interface.
Jhandai Prince, Vaddadi Kishore, Liu Lin
The Journal of general virology · 2026
PMID: 42423068
NAD + modulates REST isoform expression and its downstream mitophagy in Alzheimer's disease.
Lagartos-Donate Maria J, Escobar-Doncel Beatriz, Zhang Caroline Shi-Qi et al.
Autophagy · 2026
PMID: 42129544
NAD + supply and redox state limit developmental speed in the Drosophila eye.
Veits Nisha, Guo Yuting, He Jingjing et al.
The EMBO journal · 2026
PMID: 42489969
NAD⁺ biology and supplementation: From mechanisms to clinical perspectives.
Pandolfi Sergio, Ghezzi Charlye, Björklund Geir et al.
Molecular biology reports · 2026
PMID: 42422596
NAD+ metabolic collapse and arrest of epithelial development in Hirschsprung disease.
Zhao Yitong, Yang Jielin, Li Bo et al.
World journal of pediatric surgery · 2026
PMID: 42206947
NAMPT Deficiency Promotes Endothelial-Mesenchymal Transition by Inhibiting Energy Metabolism and Lysosomal Acidification in Late-Onset Fuchs Endothelial Corneal Dystrophy.
Xie Luoying, Chen Mingxiong, Wu Jie et al.
Investigative ophthalmology & visual science · 2026
PMID: 42500587
Navigating the Metabolic-Genomic Paradigm: Mitochondrial Reprogramming as a Driver of Cancer Plasticity.
Tzeng Yen-Dun Tony, Wen Chen-Yueh, Yong Su-Boon et al.
Oncology research · 2026
PMID: 42499551
Niacin alleviates cerebral microvascular endothelial cell apoptosis induced by hypervirulent Klebsiella Pneumoniae by reducing the accumulation of reactive oxygen species.
Zhao Yinghai, Wang Mubin, Che Xing
Frontiers in cellular and infection microbiology · 2026
PMID: 42331207
Nicotinamide N-methyltransferase as a stress-responsive metabolic-epigenetic regulator of tubular senescence in chronic kidney disease.
Liu An, Zhu Xiao-Juan, Sun Wei-Dong et al.
Cellular signalling · 2026
PMID: 42170103
Nicotinamide mononucleotide stimulates the activity of bursting slow-oscillation neurons in the supramammillary nucleus and enhances REM sleep.
Cissé Youssouf, Brace Cynthia S, Hsu Virginia et al.
iScience · 2026
PMID: 42211736
Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial.
Holmes Holly E, Srivastava Kamal, Scalici Jennifer M et al.
Frontiers in aging · 2026
PMID: 42328457
Nicotinamide riboside reduces glial inflammation and boosts mitochondrial function.
Yangzom Tsering, Chen Anbin, Lundberg Bjørn Christian et al.
International journal of biological sciences · 2026
PMID: 42300615
Non-ethanol components of Baijiu alleviate ethanol-induced energy metabolism disorder and gut microbiota dysbiosis in mice.
Gao Yingrui, Zhao Weiman, Tong Ruonan et al.
Food & function · 2026
PMID: 42423901
Open-Sourced In Silico Drug Screening.
Fikes Audrey G, Srougi Melissa C
Methods in molecular biology (Clifton, N.J.) · 2026
PMID: 42292716
Opposing Molecular Programs in Obsessive-Compulsive Disorder and Hoarding: Transcriptome-Wide Association Studies Reveal Distinct Senescence, Complement, and Metabolic Signatures.
Cheung Ngo
Cureus · 2026
PMID: 42530810
Oral LNAD+ rapidly elevates whole blood intracellular NAD and metabolic flux without elevating plasma NAD: evidence from a randomized controlled trial.
Kornilov Sergey A, Hastings Waylon J, McGrath Lynne Fahey et al.
GeroScience · 2026
PMID: 42244614
Phage RyR-domain proteins degrade ADPR-based immune signals and fuel NAD + synthesis.
López Rivera Miguel, Chang Renee B, Lewis Colin M et al.
bioRxiv : the preprint server for biology · 2026
PMID: 42336773
Photoaging of Facial Scrub Microbeads Causes Neurobehavioral Impairment in Zebrafish Larvae through Mitochondrial Dysfunction and Neurotransmission Disruption.
Ding Ping, Zhang Jiayi, Li Xin et al.
Environmental science & technology · 2026
PMID: 42134761
Poliumoside alleviates oxidative stress and improves mitochondrial function to alleviate ischemic stroke injury.
Qin Rui, Han Bo-Wen, Tao Jing-Ying et al.
European journal of pharmacology · 2026
PMID: 42570824
Polystyrene nanoplastics induce fetal growth restriction via a novel NMNAT3 depletion cascade disrupting placental mitochondrial energetics and activating ferritinophagic ferroptosis.
He Yijing, Sun Qinfeng, Yang Qianqian et al.
Free radical biology & medicine · 2026
PMID: 42389443
Postbiotic metabolites from Bifidobacterium adolescentis alleviates doxorubicin-induced aging in canine vascular endothelial cells.
Jin Hongchen, Bai Huasong, Liu Tong et al.
Experimental and therapeutic medicine · 2026
PMID: 42292711
Posttraumatic Stress Disorder (PTSD) NAD/Sirtuin Deficiency and SARM1-Mediated Synaptic Vulnerability: Evidence for Accelerated Brain Aging Subtypes.
Cheung Ngo
Cureus · 2026
PMID: 42573124
Potential Involvement of Redox and Inflammatory Signalling in the Antihyperglycemic and Antioxidant Effects of Harmaline in Male Mice With Type 2 Diabetes.
Malekinia Farima, Ahangarpour Akram, Hoseinynejad Khojasteh et al.
Endocrinology, diabetes & metabolism · 2026
PMID: 42292811
Preliminary exploration of acute limit toxicity testing for nicotinamide mononucleotide in the neonatal population.
Cao Hongting, Ge Xinyu, Cui Mingxuan et al.
Frontiers in pharmacology · 2026
PMID: 42333387
Prospects for Neuroprotective Therapies in Glaucoma: Drug Targets and Emerging Clinical Strategies.
Rho Seungsoo, Williams Pete A
Drug design, development and therapy · 2026
PMID: 42423086
Pyridinium amidate (PYA) substituents impact ligand-centered hydride formation and (catalytic) hydride transfer reactivity.
Monte Laura, Lentz Nicolas, Albrecht Martin
Dalton transactions (Cambridge, England : 2003) · 2026
PMID: 42243876
Raw defines a TIR-fold cADPR hydrolase cooperating with dSarm in development and axon degeneration.
Chen Feng, Chen Zhuo, Tan Yongjun et al.
Cell communication and signaling : CCS · 2026
PMID: 42574365
Real-Time Two-Photon Imaging of Brain Endothelial NAD+ Metabolism in Mice.
Zhan Rui, Li Yanyan, Meng Xia et al.
Journal of visualized experiments : JoVE · 2026
PMID: 42575478
Redox-guided dynamic regulation for enhanced bioproduction using engineered NADH/NAD⁺ biosensors.
Zhang Jianli, Gan Qi, Gong Xinyu et al.
Bioresource technology · 2026
PMID: 42135576
Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.
Pan Jun-Ping, Wang Ping-Jie, Zhang Jianying et al.
Nature aging · 2026
PMID: 42210432
Reproductive aging drives deterministic microbiota assembly to mitigate uterine oxidative phosphorylation impairment via spermidine production in laying hens.
Dai Dong, Long Cheng, Ma Kaixuan et al.
Microbiome · 2026
PMID: 42490155
Reprogramming Glutathione-Binding Proteins into Artificial Photoenzymes by Engineered Glutathione-Type Cofactors.
Wang Chang, Yu Jinmeng, Chen Hongwei et al.
Journal of the American Chemical Society · 2026
PMID: 42171986
Repurposing Syrosingopine for Cancer Therapy: Lactate Trapping and ISR Sensitization as Metabolic Vulnerabilities.
Javidan Moslem, Jafari Zahra, Abbasiniya Shahdokht et al.
Oncology and therapy · 2026
PMID: 42381233
Riboflavin Salvage Supports Glycolysis in Borrelia burgdorferi Through Flavin-Dependent NAD + Regeneration.
Schulz Anna M, Easterling Grace E, Balasubramaniyan Aaditya et al.
Molecular microbiology · 2026
PMID: 42544484
Roles of Sirtuin-1 in the Prevention of Intracranial Aneurysm Rupture in Mice.
Sato Hiroki, Ikedo Taichi, Take Yushiro et al.
Hypertension (Dallas, Tex. : 1979) · 2026
PMID: 42380289
SARM1 base-exchange inhibitors induce SARM1 activation and neurodegeneration at low doses.
Mani Anisha, Mendel Mateusz, Westwood Paul et al.
npj drug discovery · 2026
PMID: 42501855
SARM1-Dependent Antimetabolic Cancer Therapy.
Molli Alice, Buonvicino Daniela, Lapucci Andrea et al.
Cancer letters · 2026
PMID: 42538899
SIRT1 remodels astrocyte metabolism and promotes viral replication during neurotropic orthoflavivirus infection.
Angel Juan P, Alzate Diego, Lindman Marissa et al.
bioRxiv : the preprint server for biology · 2026
PMID: 42256526
SIRT1: Protean roles at the nexus of health, disease, and therapeutics.
Chaqour Brahim
Journal of cell communication and signaling · 2026
PMID: 42212315
SIRT3 activation by oroxylin A phosphate diethyl ester triggers mitochondrial dysfunction and apoptosis in non-small cell lung cancer.
Lee Chiang-Wen, Lin Yu-Feng, Lee Kuan-Han et al.
International journal of biological sciences · 2026
PMID: 42427712
SIRT5-dependent regulation of ASL controls arginine metabolism and T cell function.
Han Kim, Klein Rachael J, Wu Kaiyuan et al.
bioRxiv : the preprint server for biology · 2026
PMID: 42419492
Salicylate esters inhibit human and rat 11β-Hydroxysteroid dehydrogenase type 2: Mechanistic insights from enzyme kinetics, SPR, and molecular modeling.
Dai Yinwei, Chen Zhuoqi, Ren Xiya et al.
Toxicology and applied pharmacology · 2026
PMID: 42325507
Sarcopenia and satellite cell homeostasis disruption: the dual function of NAD+ metabolism.
Li Chenyuan, Ai Yue, Yan Jieni et al.
Frontiers in nutrition · 2026
PMID: 42380373
Scutellaria baicalensis root-derived silver nanoparticles for enhanced Baicalin's biological activities to inhibit breast cancer cells.
Ali Adil, Upadhyay Tarun Kumar
Scientific reports · 2026
PMID: 42429103
Selective serotonin reuptake inhibitors modulate adenylate homeostasis and redox status in human endothelial cells.
Jarczewski Jakub, Mucha Patryk T, Dumała Sylwester et al.
Nucleosides, nucleotides & nucleic acids · 2026
PMID: 42291835
Sex-specific differences in vascular circulation and metabolic regulation associated with aging and cardiovascular health problems.
Marcinek Andrzej, Katarzynska Joanna, Gebicki Jerzy
Frontiers in aging · 2026
PMID: 42296803
Short-term plasticity and long-term transcriptomic rewiring under natural ocean acidification in an ecosystem-relevant sea urchin.
Arranz V, Fernandez-Vilert R, Hernández J C et al.
Marine pollution bulletin · 2026
PMID: 42256306
Sigma-1 receptor promotes glycolysis in neuronal systems by suppressing GRIM19.
Couly Simon, Yasui Yuko, Grammatikakis Ioannis et al.
iScience · 2026
PMID: 42578857
Simultaneous Quantification of Hundreds of Phosphorylated Metabolites in Multiple Biological Matrices with Ion-Pairing Reversed-Phase Ultrahigh-Performance Liquid Chromatography and Mass Spectrometry.
Wang Huan, Yang Dandan, Wang Qi et al.
Analytical chemistry · 2026
PMID: 42327495
Sirt1 transgene delivery improves diabetes-impaired wound healing.
Luo Ruyue, Wang Huifeng, Duan Chongwen et al.
Bioactive materials · 2026
PMID: 42539047
Sirtuin 1 Is Required for Optimal Mammarenavirus Multiplication.
Witwit Haydar, Khafaji Roaa, Mingo-Casas Patricia et al.
bioRxiv : the preprint server for biology · 2026
PMID: 42133650
Skin Aging and Mitochondrial Dysfunction: Structural Changes, Mechanistic Insights, and Therapeutic Perspectives.
de Afonso Bonotto Nathália Cardoso, Musachio Elize, Felin Giulliano Danezi et al.
Oxidative medicine and cellular longevity · 2026
PMID: 42253323
Sodium Copper Chlorophyllin Inhibits Porcine Reproductive and Respiratory Syndrome Virus Infection Through Multiple Antiviral Mechanisms.
Wang Xinrong, Zhang Juan, Rui Li et al.
Transboundary and emerging diseases · 2026
PMID: 42257271
Stattic administration plays a protective role in a lipopolysaccharide-induced acute lung injury cell model.
Li Bingshu, Liu Chenchen, Li Huanxia et al.
Cell cycle (Georgetown, Tex.) · 2026
PMID: 42464969
Stereoselective Reproductive and Intergenerational Toxicity of Prothioconazole in Female Zebrafish: Concurrent Ovarian Cytotoxicity and Endocrine Disruption.
Bian Jinhao, Zhao Hanshuang, Xu Wenping et al.
Journal of agricultural and food chemistry · 2026
PMID: 42172904
Structural and functional characterization of SPARTA system.
Zhao Hongze, Huang Pingping, Guo Lijie et al.
Biochemical and biophysical research communications · 2026
PMID: 42164014
Symptom-Level Precision Neurology in Amyotrophic Lateral Sclerosis (ALS): Linking Microglial Pruning, Mitochondrial Nicotinamide Adenine Dinucleotide (NAD+) Compensation, and Autophagy Failure Across the Aging Spectrum.
Cheung Ngo
Cureus · 2026
PMID: 42382234
Synchronized UAV multi-angle inversion of canopy structure parameters in wheat breeding materials.
Mi Zhiwen, Su Jinya, Chen Qifan et al.
Plant phenomics (Washington, D.C.) · 2026
PMID: 42164813
Synthesis of thermostable artificial nicotinamide cofactors: carba-NAD + and carba-NADP .
Dsouza Zinnia, Friedrichs Jan-Simon Jeshua, Döring Manuel et al.
RSC chemical biology · 2026
PMID: 42503180
Synthesis, Characterization, and Fluorescence Application of Indole-Based Isofunctional NAD + Analogs.
Li Danqi, Zhuang Bo, Feng Ran-Ran et al.
Chembiochem : a European journal of chemical biology · 2026
PMID: 42490967
Targeted stool metabolomics suggests exploratory catecholamine- and tryptophan-linked metabolic features in autism spectrum disorder.
Liu Kevin, Li Huixi, Zhang Shaohan et al.
Frontiers in neuroscience · 2026
PMID: 42571993
Targeting Mitochondrial Complex I Protects Against Palmitic Acid-Induced Endothelial Dysfunction.
Zhou Chenxia, Chen Da, Li Ruoxuan et al.
Diabetes, obesity & metabolism · 2026
PMID: 42467143
Targeting Sirtuin Signaling in Parkinson's Disease and Neurodegeneration: Molecular Insights and Translational Potential.
Kumari Shobha, Singh Hemraj, Vaidya Shravani et al.
Molecular neurobiology · 2026
PMID: 42208839
Targeting promoter G-quadruplex of SIRT3 with valsartan and candesartan as a therapeutic strategy to downregulate its expression in lung cancer.
Chetia Pronamika, Kumar Amit
International journal of biological macromolecules · 2026
PMID: 42492380
Targeting the NAD + salvage pathway: Identification of bifunctional NAMPT inhibitors and SIRT1 activators through pharmacophore-based virtual screening.
Ozgencil Fikriye, Almamis Selen Ozge, Cimen Huseyin et al.
Bioorganic & medicinal chemistry · 2026
PMID: 42461409
Targeting the NAD+ salvage pathway blocks metabolic recovery and enhances β-lapachone toxicity in NQO1-expressing glioblastoma cells.
Chang-Gu Bruce, Baljinnyam Tuvshintugs, Sowers Mark L et al.
Cancer research communications · 2026
PMID: 42390160
The Role of Nrf2 in SIRT1-Mediated RGC Neuroprotection in Traumatic Optic Neuropathy.
O'Neill Nuala, Sarabu Neha, Abd Alhadi Suad et al.
Translational vision science & technology · 2026
PMID: 42495453
The Role of Oxidative Stress in Heart Failure: Mechanisms and Therapeutic Targets.
Hussain Taha, Pandey Asmi, Karki Dipesh et al.
Cureus · 2026
PMID: 42533106
The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming.
Cole Aidan R, Buj Raquel, Uboveja Apoorva et al.
Nature aging · 2026
PMID: 42383757
The human gut microbe Eubacterium limosum utilizes flavodoxin over ferredoxin for lactate metabolism.
Putumbaka Saisuki, Shao Nana, Donaghy Aaron P et al.
Applied and environmental microbiology · 2026
PMID: 42133993
The mitochondrial genome of pequi tree (Caryocar brasiliense Cambess.): Genome structure, gene transfers, and evolutionary insights within Malpighiales.
Carvalho Larissa R, Corvalan Leonardo N, Dias Renata O et al.
Genome · 2026
PMID: 42459658
The mitochondrial logic of inflammaging: how energy imbalance drives fibroblast SASP and tissue-specific aging.
Huan Yu, Wang Qiqi, Fang Rongkaixuan et al.
Frontiers in immunology · 2026
PMID: 42389755
The myofascial rheostat: hyaluronan molecular weight dynamics and purinergic signalling as a physiological feedback system.
Kirkness Karen B, da Silva Fabiana C, Schleip Robert et al.
Frontiers in physiology · 2026
PMID: 42294629
The nicotinamide phosphoribosyltransferase inhibitor FK866 restricts influenza A virus replication by perturbing viral polymerase activity.
Lv Changjie, Wang Shuang, Song Mingyue et al.
Journal of virology · 2026
PMID: 42138716
The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.
Lefrançois Guillaume, Lavallée Emilie, Rowell Marie-Camille et al.
eLife · 2026
PMID: 42294340
The role of NAD + metabolic reprogramming in colorectal cancer chemoresistance: mechanistic insights, clinical translation challenges and opportunities.
Ma Zhennan, Gong Xiuqing, Liu Fuquan
Frontiers in oncology · 2026
PMID: 42380286
Therapeutic effect of intranasal nicotinamide adenine dinucleotide in the restoration of olfactory dysfunction.
Yoo Shin Hyuk, Jang Jung Yeon, Bae Jun-Sang et al.
Experimental & molecular medicine · 2026
PMID: 42325660
Thermodynamic metabolic modeling of growth and bioproduction potential of the acetogen Acetobacterium woodii with and without redox cofactor swaps.
Bauer Jasmin, von Kamp Axel, Pflügl Stefan et al.
Synthetic and systems biotechnology · 2026
PMID: 42216313
Thioredoxin system modulates metabolic and stomatal responses to elevated CO 2 in Arabidopsis.
da Fonseca-Pereira Paula, Mélo Neto Domingos F, Monteiro-Batista Rita de Cássia et al.
The New phytologist · 2026
PMID: 42253138
Third Generation Genome Sequencing of the Endobacterium Corynebacterium kroppenstedtii subsp. demodicis Reveals Details of Its Microbe-Host-Interaction With the Most Complex Human Commensal, Demodex folliculorum.
Steegmüller T, Walch S, Gschwendtner S et al.
Environmental microbiology reports · 2026
PMID: 42501334
Tracing NAD + metabolism uncovers adaptive coordination between host and microbiome during colitis.
Alsaadi Abrar I, Wehkamp Lina, Pothakamury Anant A et al.
Cell reports · 2026
PMID: 42212397
Transcriptional Modulation of the Nrf2 Antioxidant Pathway and Tight Junctions by a Plant Sterol Food Supplement in an Intestinal Inflammation Coculture Model.
Makran Mussa, Giardina Ilenia Concetta, Garcia-Llatas Guadalupe et al.
Journal of food science · 2026
PMID: 42457559
Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects.
Li Jing, Lin Yang-Chi-Dung, Huang Hsi-Yuan et al.
Phytotherapy research : PTR · 2026
PMID: 42491287
Tryptophan-Enriched Lactobacillus rhamnosus GG-derived Nanovesicles Promote Alveolar Bone Regeneration through Macrophage Fatty Acid Oxidation.
Huang Zhendong, Liu Yuqi, Yang Qiudong et al.
Biomaterials research · 2026
PMID: 42537350
USP10-SIRT6-PARP1 axis drives keratinocyte senescence and skin photoaging under chronic UVA exposure.
Zhang Yuxi, Zuo Xulei, Hou Xiaoyu et al.
International immunopharmacology · 2026
PMID: 42250718
Use of UDP-glucose-4-epimerase all4713 from Nostoc sp. PCC 7120 in the synthesis of galactose.
Huo Wen, Sayed Hend, Liu Miao et al.
Archives of biochemistry and biophysics · 2026
PMID: 42489713
Using a liver-on-chip model to evaluate the effects of vancomycin and daptomycin on host immunometabolism and clearance of intracellular reservoirs of Staphylococcus aureus during bacteremia.
Beadell Brent, Yi Sujung, Roberts Makayla et al.
Antimicrobial agents and chemotherapy · 2026
PMID: 42421422
Visualizing NO 2 - /NAD(P)H metabolic crosstalk in E. coli -infected bladder cancer via a dual-responsive probe.
Guan Jiayun, Jiang Xusheng, Lv Yilin et al.
Chemical communications (Cambridge, England) · 2026
PMID: 42457548
Vladimiria souliei Ameliorated Aspirin-Induced Gastric Mucosal Injury by Activation Nrf2 and Inhibition RIP1 Signaling Pathways.
Zhao Binjing, Jiang Xinyi, Wei Xiaojing et al.
Biological & pharmaceutical bulletin · 2026
PMID: 42135540
Whole-blood NAD + levels do not reflect healthy ageing.
Nature metabolism · 2026
PMID: 42429483
YAP Regulates the Nrf2 Signaling Axis to Attenuate Oxidative Stress and Neuroinflammation in Retinal Ganglion Cell Degeneration.
Zhou Shirui, Yang Fumin, Ding Ke et al.
Investigative ophthalmology & visual science · 2026
PMID: 42544650
[Daporinad Potently Induces Cell Death in Ph + Acute Lymphoblastic Leukemia SUP-B15 Cells Independent of the Intrinsic Apoptotic Pathway].
Xi Jing-Jing, Wang Cong-Yue, Zhan Jia-Min et al.
Zhongguo shi yan xue ye xue za zhi · 2026
PMID: 42128686
[Development and application of amplification-free nucleic acid detection in molecular diagnostics].
Cao H, Guo S F, Yang B et al.
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] · 2026
PMID: 42502934
[Sirtuins as geroprotectors and epigenetic regulators of cell cycle.].
Belova Y I, Khabarov V N, Kvetnaya T V
Advances in gerontology = Uspekhi gerontologii · 2026
PMID: 42325566
q orA shapes organ-specific adaptation of ST59-MRSA via balancing immune evasion and metabolic trade-off.
Chen Fengning, Yin Yuyao, Liu Si et al.
iScience · 2026
For research use only. This index links to third-party literature. Nothing here constitutes medical advice.