Research Library

MK-677

21 papers indexed

PMID: 41260416

Acute stress suppresses hunger-driven food seeking through PVN activation: Reversal by anxiolytic drug and ghrelin receptor agonist, with anxiolytic-like effects of refeeding.

Tojo Ryusei, Tashiro Mayuka, Takahashi Haruka et al.

Neuroscience research · 2026

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PMID: 42578445

Peptide Supplements and Their Therapeutic Applications in Sports Medicine.

Tewari Kushagra, Liu Timothy P, Im Christina et al.

The American journal of sports medicine · 2026

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PMID: 42064485

Spontaneous Splenic Rupture in a Patient With Recent Use of Performance-Enhancing Compounds: A Case Report and Literature Review.

Jaffry Kumail, Shah Jainam, Naqash Niyaz

Cureus · 2026

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PMID: 40675653

Hepatotoxicity induced by MK-677.

Cobani Era, Amin Md Shahnoor, Hasso Muneer et al.

BMJ case reports · 2025

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PMID: 40882886

Knowing the minimal detectable dose can facilitate the interpretation of a hair test result: II. Case example with ibutamoren (MK-677), a growth hormone secretagogue.

Kintz Pascal, Gheddar Laurie

Clinica chimica acta; international journal of clinical chemistry · 2025

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PMID: 39145153

Reversible Gynecomastia and Hypogonadism Due to Usage of Commercial Performance-Enhancing Supplement Use.

Chong Serena, Woolnough Catherine A, Koyyalamudi Sundar R et al.

JCEM case reports · 2024

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PMID: 34814052

Development and validation of SARMs and metabolic modulators screening in hair using UHPLC-MS/MS: Application to a doping case and first identification of S23 in authentic human hair.

Gheddar Laurie, Raul Jean-Sébastien, Kintz Pascal

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2022

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PMID: 36303408

LGD-4033 and MK-677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report.

Cardaci Thomas D, Machek Steven B, Wilburn Dylan T et al.

Experimental physiology · 2022

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PMID: 32814069

Brain and kidney GHS-R1a underexpression is associated with changes in renal function and hemodynamics during neurogenic hypertension.

Sales da Silva Elder, Ferreira Patrícia Maria, Castro Carlos Henrique et al.

Molecular and cellular endocrinology · 2021

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PMID: 33934684

Development and validation of liquid chromatography-tandem mass spectrometry method for screening six selective androgen receptor modulators in dietary supplements.

Lee Ji Hyun, Han Ji Hye, Jung Eun-Ju et al.

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment · 2021

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PMID: 30450851

Effect of the Orally Active Growth Hormone Secretagogue MK-677 on Somatic Growth in Rats.

Lee Junghun, Kwon Ahreum, Chae Hyun Wook et al.

Yonsei medical journal · 2019

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PMID: 19625579

Growth hormone secretagogues and growth hormone releasing peptides act as orthosteric super-agonists but not allosteric regulators for activation of the G protein Galpha(o1) by the Ghrelin receptor.

Bennett Kirstie A, Langmead Christopher J, Wise Alan et al.

Molecular pharmacology · 2009

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PMID: 18923064

Overlapping binding site for the endogenous agonist, small-molecule agonists, and ago-allosteric modulators on the ghrelin receptor.

Holst Birgitte, Frimurer Thomas M, Mokrosinski Jacek et al.

Molecular pharmacology · 2009

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PMID: 18981485

Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial.

Nass Ralf, Pezzoli Suzan S, Oliveri Mary Clancy et al.

Annals of internal medicine · 2008

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PMID: 18553971

Electrophile-induced dearomatizing spirocyclization of N-arylisonicotinamides: a route to spirocyclic piperidines.

Arnott Gareth, Brice Heloise, Clayden Jonathan et al.

Organic letters · 2008

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PMID: 19015485

Growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial.

Sevigny J J, Ryan J M, van Dyck C H et al.

Neurology · 2008

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PMID: 15905359

Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling.

Holst Birgitte, Brandt Erik, Bach Anders et al.

Molecular endocrinology (Baltimore, Md.) · 2005

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PMID: 12550076

The effect of treatment with the oral growth hormone (GH) secretagogue MK-677 on GH isoforms.

Svensson J, Boguszewski C L, Shibata F et al.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2003

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PMID: 11741481

Oxindole derivatives as orally active potent growth hormone secretagogues.

Tokunaga T, Hume W E, Umezome T et al.

Journal of medicinal chemistry · 2002

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PMID: 11739014

Pharmacological profile of a new orally active growth hormone secretagogue, SM-130686.

Nagamine J, Nagata R, Seki H et al.

The Journal of endocrinology · 2002

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PMID: 11669462

Role of endothelial cells in modulation of contractility induced by hexarelin in rat ventricle.

Bedendi I, Gallo M P, Malan D et al.

Life sciences · 2001

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For research use only. This index links to third-party literature. Nothing here constitutes medical advice.