L-Carnitine

PMID: 42021759

A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation.

Dörner Sebastian, Rogge Kai, Trottmann Felix et al.

Angewandte Chemie (International ed. in English) · 2026

PMID: 42065149

A child with cobalamin C deficiency caused by complex heterozygous variation of c.567dupT and c.80A > G complicated with pulmonary arterial hypertension and hydrocephalus: A case report and literature review.

Cui Xuxia, Zhong Yajing, Yin Chongjuan

Medicine · 2026

PMID: 42165308

A systematic review on pharmacotherapy of post-traumatic attention impairments.

Kim Sonya, Sood Pallavi, Gopaul Urvashy et al.

Brain injury · 2026

PMID: 42087912

A translational mechanistic synthesis of ischemia-reperfusion injury in experimental flap models toward free flap salvage.

Akdemir Ovunc

Frontiers in surgery · 2026

PMID: 42376093

Acetyl-L-carnitine protective role in gemcitabine-induced neurotoxicity in an experimental rat model.

Majed Marwa Sabah, Al-Kafhage Fatema Ali, Alameri Hiba et al.

Open veterinary journal · 2026

PMID: 42115271

Altered gut microbiota and metabolites in children with non-organic anorexia: a multi-omics integration study.

Li Zonglong, Zhang Qiong, Yang Jin et al.

Scientific reports · 2026

PMID: 42455388

Antioxidant Effects of Vitamin E and L-Carnitine on Hippocampal Histology, Epigenetics, and Cognition in Morphine-Exposed Mice.

Alizadeh Marzieh, Haghpanah Tahereh, Ezzatabadipour Massood et al.

Molecular neurobiology · 2026

PMID: 42385949

Bacopa-enriched formulation enhances memory and synaptic plasticity in a rat model of vascular dementia.

Yunusa Suleiman, Halimi Nur Sabrina, Abdullah Muhammad Hazim et al.

Behavioural brain research · 2026

PMID: 42219940

Bio-Ionic Liquid-Induced Rapid Self-Initiating Tough Ionogels for In Situ Adhesion.

Yu Junjie, Xiong Jiaofeng, Wu Bingyang et al.

Advanced materials (Deerfield Beach, Fla.) · 2026

PMID: 42356803

Biochemical Signatures of L-Carnitine-Induced Changes in Brain Cancer Cells Revealed by Confocal Raman Imaging: A Preliminary Study.

Surmacki Jakub Maciej, Sergot Krzysztof, Kopeć Monika

Sensors (Basel, Switzerland) · 2026

PMID: 42560722

Boosting HSC functions: l-carnitine takes center stage.

Filippi Marie-Dominique

Blood · 2026

PMID: 42174096

Changes in hepatic L-carnitine levels in people with metabolic dysfunction-associated steatotic liver disease (MASLD) assessed by magnetic resonance techniques.

Savic Dragana, Pavlides Michael, Kjær Mette Skalshøi et al.

Scientific reports · 2026

PMID: 42105943

Chemical and biochemical derivates of trans-3-methylglutaconyl CoA: A molecular labyrinth.

Jennings Elizabeth A, Jones Dylan E, Ryan Robert O

Clinica chimica acta; international journal of clinical chemistry · 2026

PMID: 42253799

Clinical outcomes of mitochondrial-enhancing nutraceutical supplementation in psychiatric disorders: A systematic review.

Tortajada Juan, Bulduk Bengisu Kevser, Alfonso-Landete Belén et al.

General psychiatry · 2026

PMID: 42352087

Clonal Hematopoiesis and Gut Microbiota-Derived TMAO as Candidate Amplifiers of Cardiovascular Inflammation: The CHIDT Hypothesis.

Caradonna Eugenio, Ferrara Fulvio, Costantino Lucy et al.

Antioxidants (Basel, Switzerland) · 2026

PMID: 42443839

Coexistence of VLCAD deficiency and Hashimoto's thyroiditis: a rare case report.

Gunay Yasemin Emur, Aydın Gokhan, Dulger Ahmet Cumhur

BMC endocrine disorders · 2026

PMID: 42280358

Comparative Analysis of L-Carnitine and Coenzyme Q 10 Adverse Reaction Reports Using the EudraVigilance Database: Implications for Health and Sports Supplementation.

Di Mauro Debora, Calapai Fabrizio, Ammendolia Ilaria et al.

Nutrients · 2026

PMID: 42261369

Current Evidence of Acetyl-L-Carnitine Use in Mood Disorders-: A Systematic Review and Meta-Analysis.

Kumar Rakesh, Hashempour Zahra, Shahriarirad Sara et al.

Neuropsychiatric disease and treatment · 2026

PMID: 42431282

Danshen-Chuanxiong alleviates cerebral ischemia by regulating carnitine metabolism and angiogenesis via activating CPT1/HIF-1α signaling axis.

Pang Han-Qing, Zhang Xuan-Hao, Zhang Jia-Le et al.

Journal of ethnopharmacology · 2026

PMID: 42385216

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma.

Wang Muyun, Hu Haiyang, Wang Kun et al.

Allergy · 2026

PMID: 42171752

Deleterious in vitro effects of ammonia and accumulated urea cycle amino acids on leukocyte DNA: assessment of the antioxidant effects of N-acetylcysteine and L-carnitine.

Lopes Franciele Fátima, Faverzani Jéssica Lamberty, Dos Reis Bianca Gomes et al.

Naunyn-Schmiedeberg's archives of pharmacology · 2026

PMID: 42306370

Dilated Cardiomyopathy in Children: A Diverse Etiological Profile.

Setouani Soukayna, Mehdaoui Asmae, Hazzab Nidale et al.

Cureus · 2026

PMID: 42314964

Dose-dependent modulation of mitochondrial physiology and nutrient secretion in Sertoli cells by l-carnitine.

Mateus Filipa G, Martins Ana D, Moreira Silvia et al.

Toxicology and applied pharmacology · 2026

PMID: 41996561

Dual-Lock NIR Dual-Channel Probe: Synchronous Viscosity/HSO 3 - Sensing for Visualizing Platinum-Induced Nephrotoxicity and Renoprotector Screening.

Gao Siyu, Zhang Lulu, Li Wenwen et al.

Analytical chemistry · 2026

PMID: 42304183

EXPRESSION OF CONCERN: Hypoxia-Induced Deactivation of NGF-Mediated ERK1/2 Signaling in Hippocampal Cells: Neuroprotection by Acetyl-L-Carnitine.

Journal of neuroscience research · 2026

PMID: 42117948

Eco-Friendly Synthesis of L-Carnitine-Loaded β-Cyclodextrin-Functionalized N-Doped Carbon Dots Using Rhododendron Species: Antioxidant and Antimicrobial Activities and In Vivo Acute Toxic Effects on Nauplii.

Özkan Yeşim, Akyol Aleyna

Nanomaterials (Basel, Switzerland) · 2026

PMID: 42316068

Effect of L-carnitine supplementation on cardiac-metabolic risk factors in hemodialysis patients: a systematic review and meta-analysis of clinical trials.

Vajdi Mahdi, Adeli Shaghayegh, Noshadi Nooshin et al.

BMC nephrology · 2026

PMID: 42293209

Effect of a polyphenol-rich pomegranate extract on plasma trimethylamine N-oxide levels following an oral carnitine challenge: a randomized controlled crossover trial in healthy adults.

Haarhuis Julia E, Ahn-Jarvis Jennifer, Savva George M et al.

Frontiers in nutrition · 2026

PMID: 42257987

Effect of adding sorbitol and/or L-carnitine to dairy goat' diets on some metabolic parameters and productivity performance.

Sadek Ahmed M A, Grawish Sara I, Madkour Marwa A et al.

Tropical animal health and production · 2026

PMID: 42364536

Effects of rumen fluid transplantation on longissimus dorsi muscle development in Xizang sheep: An association analysis based on transcriptomic and serum metabolomic profiles.

Pan Junru, Chen Tingxian, Pan Cheng et al.

Comparative biochemistry and physiology. Part D, Genomics & proteomics · 2026

PMID: 42212264

Energy metabolic dysregulation in heat stroke: from mitochondrial dysfunction to multi-organ failure mechanisms and targeted intervention.

Li Qiqi, Wang Jinquan, Qin Xiaojie et al.

Frontiers in pharmacology · 2026

PMID: 42504863

Enhanced metabolic flexibility links Mediterranean diet with cognition: interim findings from a randomized controlled trial.

Cruz Meryl, Martínez-Huélamo Miriam, Yubero-Serrano Elena M et al.

Food & function · 2026

PMID: 42105529

Feeds supplemented with L-carnitine and varying oil sources improve the Rhamdia quelen thawed sperm redox balance and sperm movement.

Baumgartner Leonardo Aluisio, Cardoso Sara Ugulino, da Silva Weverson Ailton et al.

Cryobiology · 2026

PMID: 42148943

Fermented goat milk powder promotes intestinal development and enhances splenic antioxidant function in mice.

Fan Liaoyu, Sha Kela, Zhang Hui et al.

Food & function · 2026

PMID: 42142608

Forest-cultivated Epimedium koreanum Nakai mitigates organotin-induced renal injury and the exacerbation of diabetic nephropathy via the SIRT1/NRF2/PPARγ signaling pathways.

Hou Jingang, Han Lu, Liu Siyu et al.

Chemico-biological interactions · 2026

PMID: 42158052

GPX4 regulates lipid peroxidation and ferroptosis of stored red blood cells.

Stephenson Daniel, Keele Gregory R, Hay Ariel et al.

Blood. Red cells & iron · 2026

PMID: 42025167

Glucose hypometabolism and hyperphosphorylated Tau synergistically drive neuronal necroptosis.

Chen Xiaoshi, Li Sixuan, Neubauer Antonia et al.

Neuron · 2026

PMID: 42232577

Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults.

Wang Xiaolan, Hou Ruiliang, Chen Zhihao et al.

Frontiers in nutrition · 2026

PMID: 42349767

Guilu Erxian oral liquid alleviates oligoasthenospermia via the mitochondria-complement-NETs network.

Yue Qingyun, Tong Kejin, Feng Qin et al.

Journal of ethnopharmacology · 2026

PMID: 42353505

High-Dose Aluminium Chloride Exposure Disrupts the Renal Cortical Injury-Repair Balance in Rats: Partial Modulation by L-Carnitine Pretreatment.

Abo-Zeid Faten S, Emam Wiame W M

Animals : an open access journal from MDPI · 2026

PMID: 42543538

Hydnocarpic acid and chaulmoogric acid, the principal antifungal compounds in Hydnocarpus hainanensis seed extract, inhibit fatty acid β-oxidation and suppress infection of Magnaporthe oryzae.

Zhu Yanqiu, Guo Hong, Xu Xiaozhou et al.

Pest management science · 2026

PMID: 41990905

IGF-1 attenuates high fat diet-elicited cardiomyopathy via arachidylcarnitine-dependent suppression of ferroptosis and mitochondrial dysfunction.

Wang Lin, Shen Mingzhi, Abudureyimu Miyesaier et al.

European journal of pharmacology · 2026

PMID: 42332819

Impact of L-carnitine supplementation on lipid profile parameters in overweight and obese women: a systematic review and meta-analysis of randomized controlled trials.

Yu Yongmei, Xu Dongping, Shang Siyi et al.

Nutrition & metabolism · 2026

PMID: 42375771

Impact of antioxidant and micronutrient intake on varicocele-associated infertility: a retrospective analysis.

Fu Dian, Tan Xiaowen, Zheng Zhigang et al.

Frontiers in nutrition · 2026

PMID: 42066642

Integrating machine learning and metabolomics to identify PFAS-associated metabolic alterations related to lung cancer risk.

Qu Jianli, Zhang Xinguo, Jin Qianxun et al.

Environment international · 2026

PMID: 42381567

L-Carnitine Improves Visceral Hypersensitivity and Colonic Hyperpermeability in a Rat Model of Irritable Bowel Syndrome.

Nozu Tsukasa, Miyagishi Saori, Ishioh Masatomo et al.

Neurogastroenterology and motility · 2026

PMID: 42189862

L-Carnitine Regulates Regeneration of Human Hematopoietic Stem and Progenitor Cells.

Duan Honglin, Wang Bohong, Zheng Yawei et al.

Blood · 2026

PMID: 42143848

L-carnitine ameliorates decidualization in high-fat diet-induced obese rats and human endometrial stromal cells treated with palmitic acid.

Cao Hairu, Qi Dandan, Sun Na et al.

Reproductive biomedicine online · 2026

PMID: 42523896

Levocarnitine mitigates varicocele-induced spermatogenic impairment by restoring mitochondrial integrity and redox homeostasis in rats.

Ma Gang, Huang Chuang, Zhang Bin et al.

Frontiers in cell and developmental biology · 2026

PMID: 42021207

Longitudinal metabolomics reveals dynamic associations of trimethylamine N-oxide and precursors with the progression of gestational diabetes.

Wu Yuwen, Ni Zheng, Liu Shuo et al.

BMC pregnancy and childbirth · 2026

PMID: 42174334

Management of osteoporosis in older men: a systematic review of randomized trials of pharmacological and non-pharmacological strategies.

da Rocha-Loures Marco Antonio Araújo, de Freitas Zerbini Cristiano Augusto, de Azevedo Elaine et al.

Archives of osteoporosis · 2026

PMID: 42555863

Metabolic Modulation for Liver Regeneration in Hepatocellular Carcinoma: From Biological Mechanisms to Precision Regenerative Medicine.

Okabayashi Takehiro, Tabuchi Motoyasu, Tokumaru Teppei et al.

Nutrition and cancer · 2026

PMID: 42435338

Metabolomic Factors Associated With Major Adverse Cardiovascular Events in Patients With Coronary Heart Disease: A Systematic Review and Meta-Analysis.

Li Yanyue, Liu Yuli, Shen Xiaoxuan et al.

Biological research for nursing · 2026

PMID: 42286133

Metabolomic signatures prior to in-hospital cardiac arrest: insights into potential therapeutic targets.

Lazzarin Taline, Nunes Julia S, Ballarin Raquel S et al.

Scientific reports · 2026

PMID: 42065429

Metabolomics-based study of potential biomarkers and metabolic pathways in sepsis-associated acute kidney injury.

Sun Xinyi, Li Fang, Yang Gaoyin et al.

Analytical methods : advancing methods and applications · 2026

PMID: 42024134

Mitochondrial encephalomyopathy with chronic intestinal pseudo-obstruction.

Zhang Wenzheng, Lian Huixiu, Li Jun et al.

Revista espanola de enfermedades digestivas · 2026

PMID: 42353386

Multi-Omics Analysis Reveals New Insights into Yak Lung Under High-Altitude Adaptation.

Chen Ping, Zhang Jian

Animals : an open access journal from MDPI · 2026

PMID: 42140124

Multi-omics and in silico assessment of ecological risks posed by agrochemical coatings: Disruption of rhizosphere stress signaling and induction of bulb rot in Fritillaria cirrhosa.

Lu Yi, Wu Yuhan, Zhang Haobo et al.

Ecotoxicology and environmental safety · 2026

PMID: 42211549

Multimechanistic actions of functional factors in enhancing physical strength and endurance: a scoping review of nutritional basis and natural extracts.

Huang Xiangyu, Zhu Jingjing, Zang Peng et al.

Frontiers in sports and active living · 2026

PMID: 42136265

N-acetylcysteine, Acetyl-L-carnitine, and Citicoline: A Potential Synergism in Neurological and Psychiatric Disorders.

Alborghetti Marika, Caridi Matteo, Mascio Giada et al.

Current neuropharmacology · 2026

PMID: 42332019

Niosomal l-carnitine and quercetin improve sperm quality and testicular function in atrazine-induced reproductive toxicity in rats.

Azmi Omniya E, Abdel-Wahab Ahmed, Abdel-Rahman Mootaz A M et al.

Scientific reports · 2026

PMID: 42440415

Optimizing a carbon source based on water temperature to reduce Vibrio abundance and promote beneficial bacteria in a Penaeus vannamei shrimp biofloc system in China: a preliminary study.

Ghonimy Abdallah, Chen Zhao, López Greco Laura Susana et al.

Frontiers in systems biology · 2026

PMID: 42504347

Peritoneal Dialysis in Infant Methylmalonic Acidemia: Effective Management Despite Sterile Peritonitis.

Manir Mustakiz Z, Haldar Utsav, Gopal Niranjan et al.

Cureus · 2026

PMID: 42285215

Plasma metabolomics enhances risk prediction for lung cancer: a population-based validation study.

Wang Chenran, Dong Xuesi, Zhang Guochao et al.

Cancer letters · 2026

PMID: 42418014

Plasma trimethylamine N-oxide and related metabolites and overall survival of high-grade serous ovarian cancer: a nested case-control study.

Xie Meng-Meng, Wang Ya-Li, Liu Jia-Xin et al.

European journal of nutrition · 2026

PMID: 42088855

Protective effect of dietary L-carnitine supplementation on follicular development in the ovary of ewes with subclinical pregnancy toxemia.

Turgut Ali Osman, Pekince Özöner Merve, Koca Davut et al.

Archives animal breeding · 2026

PMID: 42377452

Protective in vitro effects of antioxidants against DNA damage induced by metabolites accumulated in propionic and methylmalonic acidemias.

Dos Reis Bianca Gomes, Lopes Franciele Fátima, Tedesco Luísa Maria Bosquetti et al.

Naunyn-Schmiedeberg's archives of pharmacology · 2026

PMID: 42262326

RETRACTED: Uner et al. Assessing the In Vitro and In Vivo Performance of L-Carnitine-Loaded Nanoparticles in Combating Obesity. Molecules 2023, 28 , 7115.

Uner Burcu, Ergin Ahmet Dogan, Ansari Irfan Aamer et al.

Molecules (Basel, Switzerland) · 2026

PMID: 42429175

RETRACTION: Computational and Preclinical Evidence of Anti-ischemic Properties of L-Carnitine-Rich Supplement via Stimulation of Anti-inflammatory and Antioxidant Events in Testicular Torsed Rats.

Cellular Longevity Oxidative Medicine And

Oxidative medicine and cellular longevity · 2026

PMID: 42500735

Recent advances in the bioanalysis of acylcarnitines: Methodologies, challenges, and clinical perspectives.

Zheng Jiaxin, Chen Wanting, Qin Fengxia et al.

Pharmaceutical science advances · 2026

PMID: 42331788

Regulation of oligodendrocyte metabolism and myelination by acetyl-L-carnitine in a mouse model of post-weaning social isolation.

Yang Hyun-Jeong, Park Youngja Hwang, Kim Dalnim et al.

Translational psychiatry · 2026

PMID: 42418576

Reprogramming of valine metabolism mediated by abnormally low ALDH6A1 expression promotes invasive metastasis of gastric cancer.

Wang Jipeng, Han Lei, Li Gang et al.

Science advances · 2026

PMID: 42371477

Reversible Secondary Carnitine Deficiency Associated With Chronic Achromobacter xylosoxidans Bacteremia Presenting as Acute Metabolic Myopathy: A Case Report.

Verma Amogh, Kakru Dilip Kumar, Shridevi Kotina et al.

Clinical medicine insights. Case reports · 2026

PMID: 42071906

Rumen-Plasma-Milk Metabolomics Profiling Revealed Metabolic Alterations Associated with Milk Fat Synthesis in Chinese Holstein Cows.

Zhang Huimin, Kollie Sam Carie, Xia Tianyu et al.

Animals : an open access journal from MDPI · 2026

PMID: 42457245

Serum 1H NMR-Based Untargeted Metabolomics for Noninvasive Early Detection of Breast Cancer.

Ali Akbar, Tengku Din Tengku Ahmad Damitri Al Astani, Maulidiani Maulidiani et al.

Journal of proteome research · 2026

PMID: 42511595

Serum Metabolomics Reveals Carnitine Metabolism as a Possible Central Metabolic Axis of Pemafibrate Action.

Qian Chufang, Zhang Xuguang, Zhang Zhe et al.

International journal of molecular sciences · 2026

PMID: 42147496

Severe Hyperammonemic Encephalopathy Following Sustained-Release Sodium Valproate Overdose: A Case Report.

Ban Shotaro, Toida Chiaki, Yamazaki Maiko et al.

Cureus · 2026

PMID: 42500249

Short-term ketogenic diet induces systemic lipidomic remodeling associated with metabolic adaptation in humans.

Park Minkuk, Yu Jae Sik, Jeon Justin Y et al.

Frontiers in nutrition · 2026

PMID: 42107106

Synthesis of Amines for Active Pharmaceutical Ingredients Using the Whole-Cell Factory Saccharomyces Cerevisae.

Kwiatos Natalia, Ossel Stephen, Mutti Francesco G

Chembiochem : a European journal of chemical biology · 2026

PMID: 42420940

TANGO2-related metabolic encephalopathy-arrhythmia syndrome unmasked in 22q11.2 deletion syndrome: hemizygous pathogenic variant, complex phenotype modified by two genetic conditions, and implications for proactive crisis prevention: a case report.

Grzywna-Rozenek Ewa, Sędek Łukasz, Rydzanicz Małgorzata et al.

BMC pediatrics · 2026

PMID: 42514375

The Dynamic Coenzyme Network of B Vitamins in Nutritional Neuropathy and Neuropsychiatric Vulnerability: A Mechanistic Narrative Review.

Yoon Yonghyun, Hwang Jihyo, Park Rowook et al.

Nutrients · 2026

PMID: 42193838

The Effects of Tributyrin on Immune Function, Antioxidant Capacity, and Metabolomics in Young Pigeons.

Wu Run, Deng Lihuan, Li Haiying et al.

Animals : an open access journal from MDPI · 2026

PMID: 42241820

The OCTN2 transporter can be targeted by carnitine functionalised non-ionic surfactant vesicles to deliver drugs across the blood-brain barrier.

Bateman-Price Thomas D, Preston Jane E, Burgess Gary et al.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026

PMID: 42187750

Transcriptomic and Metabolomic Profiling Reveals the Antiproliferative Mechanism of Goose Serum and Plasma in SW1990 Cells.

Zhou Xiaolong, Wu Mihan, Wang Han et al.

Biology · 2026

PMID: 42429318

Transcriptomics Reveals L-Carnitine to Enhance Semen Quality in Malabari Bucks via Nutrigenomic Regulation of Key Biological Processes Associated With Male Fertility.

Shashikiran Doddannavar, Asaf Muhasin, Abraham Bindya Liz et al.

Reproduction in domestic animals = Zuchthygiene · 2026

PMID: 42450625

Trimethylamine N-Oxide and Impaired Spermatogenesis in the Gut-Testis Axis: A Focused Review of Current Evidence.

Zhang Xinyang, Luo Jialin, Zhang Xiang et al.

Biology · 2026

PMID: 42080665

Vincristine-Induced Craniofacial Skeletal Teratogenicity in Foetal Rabbits: Multimodal Morphometric Assessment and Partial Protection by L-Carnitine.

El Latif Alaa I Abd, El Sharaby Ashraf A, Hagras Eman M et al.

Anatomia, histologia, embryologia · 2026

PMID: 42475409

Zwitterion Additives in the Stöber Process for Particle Size Tuning and Silica Surface Decoration.

Like Bricker D, Wallingford Izabella R, Panzer Matthew J

Langmuir : the ACS journal of surfaces and colloids · 2026

PMID: 42233273

[Effect of supplementation with L-leucine, L-arginine, and L-carnitine on body composition in patients undergoing chronic hemodialysis].

Montenegro Cedeno Mónica Del Carmen, Briones Urvano Mercedes, Barria Israel et al.

Nutricion hospitalaria · 2026